Searchable abstracts of presentations at key conferences in endocrinology

ea0049gp208 | Thyroid 2 | ECE2017

Serum Interleukin-37 (IL-37) levels were increased and correlated with oxidative stress parameters in Hashimoto’s Thyroiditis (HT) patients

Ruggeri Rosaria Maddalena , Vicchio Teresa Manuela , Alibrandi Angela , Giovinazzo Salvatore , Certo Rosaria , Giuffrida Giuseppe , Trimarchi Francesco , Gangemi Sebastiano , Cristani Mariateresa

Background: IL-37, member of the IL-1 family, is a natural suppressor of immune and inflammatory responses. Increased serum IL-37 levels were observed in several autoimmune diseases, including GravesÂ’ disease. No data on TH are available from the literature.Materials and methods: We enrolled 45 euthyroid HT patients (5 M e 40 F, mean age 38.5±12.6) and 50 age- and sex-matched healthy controls. None was on LT-4 therapy. Smokers, subjects with ki...